The FTSE 100 is expected to start around 12 points lower when trading resumes this morning, taking its cue from a downbeat session on Wall street overnight and a relatively flat performance on Asian markets this morning.
The main issues driving sentiment in the UK continue to be around delivering a satisfactory Brexit trade deal, the extent and timing of the widely expected rise in interest rates and the impact of escalating tensions in Catalonia.
In the US overnight, the Dow closed 0.23% lower at 23,273.96, the S&P 500 fell 0.4% to end at 2,564.98 and the Nasdaq lost 0.64%, or 42.23 points, closing at 6,586.83.
In Asia this morning, the Nikkei was up 0.26% at 21,752.49, while the Hang Seng was flat at 28,306.81.
At around 6.05am, WTI was up 0.13% at $51.97 per barrel and Brent was 0.17% higher at $57.47 per barrel.
Gold was up 0.24% at $1,284 an ounce, while silver was 0.41% firmer.
Interim results are due from Bloomsbury Publishing, Gear4music, St James's Place and Whitbread.
Trading statements are expected from Anglo American, Bunzl, Carpetright, International Personal Finance, Reckitt Benckiser and Shoe Zone.
In addition, Brooks Macdonald, McBride, Premaitha Health and Oil & Gas Development Co are set to host shareholder meetings.