The FTSE 100 edged down 2.81 points to 7,527.09 on Thursday morning after trading on Wall Street was held back by concerns President Trump's tax reforms could be delayed.
One of the strongest risers was Lookers (LOOK), which surged 6.5% to 104.4p after saying it is on track to meet full year targets following positive trading in the third quarter and a solid result during the important month of September.
AstraZeneca (AZN) added 2.9% to 5,136.5p after announcing reported operating profits rose to $1,149m in the third quarter - up 12% on an actual basis and 9% at constant currencies.
On a less positive note, J Sainsbury (SBRY) made an underlying profit before tax of £251 million in the 28 weeks to 23 September, 9% lower than the year before as a result of wage cost inflation, price investment and the consolidation of Argos' first half losses. The stock fell 1.7% to 229.6p.
National Grid (NG.) declined 0.74% to 921.5p after reporting its adjusted profit before tax fell by 22% at actual exchange rates to £807 million in the six months to 30 September. Excluding the impact of timing, adjusted profit before tax was up 1% to £916 million.
Meanwhile, Auto Trader's (AUTO) operating profits rose by 9% to £109.6m in the six months to the end of September and pre-tax profits increased 10% to £105.4m. The share price advanced 3.4% to 364.3p.