UK stocks opened weaker on Wednesday after lower commodity prices hit mining and energy plays.
At 0858, the benchmark FTSE 100 was down 36.30 points, or 0.5%, at 7,378.12.
Rio Tinto, Glencore and Anglo American led miners lower, with falls of 2.0%, 2.0% and 1.9%, respectively. Shell and BP fell 1.5% and 1.0%, respectively.
TalkTalk tumbled 9.7% after posting a first-half loss and downgrading earnings guidance to the bottom end of the previously-stated range.
Premier Foods jumped 6% after the maker of cakes, gravy and other grocery items edged back into the black following a 6.2% increase in second-quarter revenue.
AstraZeneca added 0.6% after the US Food and Drug Administration approved a treatment for asthma.
Industrial products manufacturer Fenner also had a good morning, rising 6.7% after boosting annual operating profits by 59% and hiking its final dividend by 40%.
Experian edged back 0.3% after reporting 5% rises in revenue and operating earnings for the first half.
Wizz Air said it had signed an early-stage agreement with Airbus to the purchase 146 Airbus A320neo family aircraft, worth more than $17.2b at current list prices. Its shares slipped 1.2%
Barratt Developments fell 1.6% after it said sales rates so far this year were flat.
Card Factory shed 0.3% after revenues rose by 6.7% in the nine months to the end of October.