Weakness in the mining sector and the impact of oil majors BP (BP.) and Royal Dutch Shell (RDSB) going ex-dividend weighed on the FTSE 100.
BP retreated 2.1% to 559.9p and Shell was down 1.4% at £26.84.
Lower production and profitability at Randgold Resources (RRS) hit its shares by 8.2% to £56.
Fresnillo (FRES) and Evraz (EVR) suffered smaller falls of up to 1.8%.
The FTSE 100 declined 0.3% to 7,635.
Brent crude oil was up 0.3% at $77.44 per barrel. Copper climbed 1.2% to $3.08 per pound and gold glittered at $1,314 per ounce.
Royal Bank of Scotland (RBS) agreed to pay a $4.9bn fine to resolve a US probe into its past sale of mortgage-backed securities. The fine was smaller than anticipated and shares in the bank rose 4.3% to 288.1p.
Fashion retailer Next (NXT) was in the spotlight after upgrading full year profit guidance as spring weather lifted its first quarter sales, helping the shares strut 6.7% higher to £55.96.
Telecomms giant BT (BT.A) revealed it will cut up to 13,000 jobs in a bid to streamline the business and boost growth. Its full year results to 31 March unveiled no overall growth, further disappointing the market after a series of setbacks as the stock slumped 9% to 217p.
Outsourcing group Capita (CPI) lost 37.7% to 124.6p as the shares adjusted to its discounted £701m rights issue.
UK supermarket Morrisons (MRW) advanced 2.4% to 251.3p after smashed first quarter sales forecasts.
Shares went in the opposite direction at On The Beach (OTB), falling 12.4% to 569p on a half year sales miss and £1.1m hit from the failure of Monarch Airlines last year.
Housebuilder Barratt Developments (BDEV) was supported by robust customer demand, helping forward sales hit record levels at approximately £3.29bn between 1 January and 6 May. Shares in Barratt dipped 1.2% to 561.4p on concerns over slower UK house price growth.
Soft drink bottler Coca-Cola HBC (CCH) fizzed 3.5% higher to £25.52 on better than anticipated sales growth in its first quarter.
ITV (ITV) enjoyed a decent start to 2018 after net advertising revenue ticked 1% higher amid takeover rumours. Shares in ITV sparked up 4.1% to 157.4p.
Superdry (SDRY) plummeted 19.7% to £12.43 on a profit warning and poor store sales due to adverse weather deterring customers.