Source - LSE Regulatory
RNS Number : 9930I
ReNeuron Group plc
14 August 2019



14 August 2019




ReNeuron Group plc

("ReNeuron" or "the Company")


Grant-funded collaboration with exosome platform


ReNeuron Group plc (AIM: RENE), a UK-based global leader in the development of cell-based therapeutics, is pleased to announce that it is partnering with the University of Cardiff under a new grant-funded collaboration utilising ReNeuron's exosome-based drug delivery technology platform.


The grant has been awarded under Innovate UK's Knowledge Transfer Partnership and will fund a £250,000 collaborative programme of research to be undertaken by ReNeuron and the European Cancer Stem Cell Research Institute at Cardiff University.  The research programme will develop novel systems to enable the delivery of therapeutic nucleic acids, such as small interfering RNA (siRNA), across the blood brain barrier using ReNeuron's CTX stem cell-derived exosomes.


Delivering therapeutic compounds across the blood brain barrier remains a significant challenge - current delivery methods focus on easier-to-reach areas of the body.  Earlier data generated at ReNeuron have already demonstrated the ability of its CTX-derived exosomes to cross the blood brain barrier.  The ambition of the collaboration between ReNeuron and the University of Cardiff is to open up a new route for the delivery of therapeutic agents that have previously failed to target the brain.


Commenting on the grant award, Dr Randolph Corteling, Head of Research at ReNeuron, commented:


"We and our collaborators are delighted to have won this latest grant from Innovate UK.  We are very excited about the potential of our exosome technology platform to deliver therapeutic compounds to the brain and thereby to make a real step-change in the development of treatments against hard-to-target disorders of the central nervous system."







+44 (0)20 3819 8400

Olav Hellebø, Chief Executive Officer

Michael Hunt, Chief Financial Officer




+44 (0) 20 7466 5000

Mark Court, Sophie Wills, Tilly Abraham

Stifel Nicolaus Europe Limited

Jonathan Senior, Stewart Wallace, Ben Maddison (NOMAD and Joint Broker)

+44 (0) 20 7710 7600

N+1 Singer

Aubrey Powell, James Moat, Iqra Amin (Joint Broker)


+44 (0) 20 7496 3000

About ReNeuron


ReNeuron is a global leader in cell-based therapeutics, harnessing its unique stem cell technologies to develop 'off the shelf' stem cell treatments, without the need for immunosuppressive drugs.  The Company's lead clinical-stage candidates are in development for the blindness-causing disease, retinitis pigmentosa and for disability as a result of stroke.  ReNeuron is also advancing its proprietary exosome technology platform as a potential delivery system for drugs that would otherwise be unable to reach their site of action.  ReNeuron's shares are traded on the London AIM market under the symbol RENE.L. Further information on ReNeuron can be found at



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