Redx has entered into an agreement with Quay Pharma to manufacture the clinical trial supplies for Redx's Porcupine inhibitor (RXC004), which has the potential to tackle hard-to-treat cancers, such as pancreatic, triple negative breast and head and neck cancers. As previously reported, first-in-human studies for the Porcupine inhibitor are expected to commence in the first quarter of 2017. The novel, potent small molecule Porcupine inhibitor targets the Wnt pathway, an embryonic signalling pathway that is implicated in the maintenance of cancer stem cells associated with tumorigenesis, metastasis, recurrence and resistance in several types of cancer. It will have the potential to be taken orally by patients as a once daily dose. Quay Pharma is a UK-based world leader in contract development, manufacturing and packaging services to the pharmaceutical and biotech industries. Quay Pharma will be formulating the capsules that will be administered in Redx's trial.
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