Source - Alliance News

The following is a round-up of updates by London-listed companies, issued on Thursday and not separately reported by Alliance News:

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Sareum Holdings PLC - Cambridge-based biotechnology company developing kinase inhibitors for autoimmune diseases and cancers - Commences a phase 1a clinical trial for its SDC-1801 treatment. Says patient recruitment is in progress at clinical units in Victoria, Australia. SDC-1801 is a potential therapeutic for a number of autoimmune diseases. Says application trial follows approval by the Human Research Ethics Committee, while the application has also been acknowledged by Australia’s Therapeutic Goods Administration. Says phase 1b clinical study expected to begin in psoriasis patients in 2024.

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Nuformix PLC - London-based pharmaceutical development company targeting unmet medical needs in fibrosis and oncology via drug repurposing - Says study data indicates its NXP002 treatment alone delivers an anti-inflammatory effect, suppressing the release of inflammatory cytokines by over 90%. Adds that the treatment shows an addition anti-inflammatory effect when used with current standards of care. Says results suggest NXP002 increases efficacy of existing therapies with the benefit of inhaled delivery. Says anti-inflammatory takes only an hour to have an effect, and strong effect lasts for 12 hours, and anti-inflammatory effect is still present after 24 hours. ‘I’m absolutely delighted with the data we’ve generated over recent months - all the results we’ve achieved are as good as we could have hoped for and are the first results from advanced ’close to patient’ IPF and inflammation human tissue disease models,’ comments Executive director Dan Gooding.

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Conygar Investment Co PLC - London-based property investor and developer - Says Nottingham City Council has approved its application for the next phase of The Island Quarter development. Says application includes 23,123 square metre bioscience building, including laboratory and office space. Chief Executive Robert Ware comments: ‘We are delighted that the next phase of development has been approved. Nottingham is already home to a large number of exciting businesses in the bioscience space and this scheme will be an excellent addition to the mixed-use development we are creating at The Island Quarter’.

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Secure Trust Bank PLC - Solihull, England-based savings accounts and lending services provider - Says net lending in the first quarter of 2023 was £3.01 billion, up 17% from £2.57 billion a year ago. New business lending rose 7.2% to £523.5 million, from £488.2 million, which it says demonstrates sustained growth momentum, in spite of tightened lending criteria. Adds that its cost optimisation programme is on track to deliver £4 million in annualised savings by the end of 2023. ‘We see significant opportunity for sustainable growth in our focused market segments and are well positioned to help consumers and businesses fulfil their ambitions and to continue to grow our net lending and scale our business as we strengthen our distribution networks and relationships...Although the economic environment remains uncertain, we have started the year positively and are confident in delivering on our plans for the full year and our medium term targets,’ Chief Executive David McCreadie says.

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Artemis Resources Ltd - Perth-based based mining company, with gold, copper and cobalt projects in Australia - Says historical geology and a data review confirms that its 2020 drill programme intercepted gold mineralisation within a quartz diorite intrusion. Says drilling has defined the intrusion over 2 kilometres, with elevated gold in rock chips over a strike length of 4 kilometres. Says there may be a possible relationship with Sanukitoid granitoids identified by De Grey Mining in the Mallina basin. Adds that an induced polarisation survey will begin in May, in order to help identify sulphides at depth. Exploration Manager Luke Meter says: ‘We have a new understanding of the importance of intrusion related gold in the Pilbara, including the identification of Sanukitoid like intrusions by the GSWA in the vicinity of the Karratha Granodiorite, some 2.5 km from Lulu Creek. The significance of the historic gold mineralisation therefore becomes apparent. With the Lulu Creek reconnaissance drill holes displaying similar grade and scale to De Grey’s Diucon deposits, the potential upside for Lulu Creek is appreciable.’

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